Certain New Chemicals: Receipt and Status Information for February and March 2026

Earthjustice submitted a scientific study as an attachment to support their opposition to a new PFAS premanufacture notice. The study provides evidence that environmental exposure to PFAS may affect glucose homeostasis during pregnancy and increase the risk of gestational diabetes mellitus.

Earthjustice submitted a research brief titled "AI could create a perfect storm of climate misinformation" as an attachment to their comments. The document explores how generative AI, social media algorithms, and social bots can amplify climate misinformation and disinformation.

Faye Rice, representing NIOSH, provides technical comments on a methylene chloride risk evaluation. The agency argues that the EPA's risk assessment should better account for the hierarchy of controls, specifically by not assuming universal respirator use and by emphasizing engineering controls and substitution.

Earthjustice submitted a report and supporting documents in opposition to a new PFAS premanufacture notice. The submission highlights the environmental and health risks of PFAS, specifically citing high contamination levels near a Chemours plant in North Carolina.

Earthjustice opposes the EPA's approval of the new PFAS chemical Opteon 2P50 (P-26-0071), arguing that it presents unreasonable risks to human health and the environment. The organization highlights the chemical's persistence, toxicity, and potential to degrade into other hazardous PFAS, while also noting the disproportionate burden on fenceline communities.

Earthjustice submitted a toxicological profile for perfluoroalkyls as an attachment to their comments opposing a new PFAS premanufacture notice. The document provides a comprehensive review of the toxicologic and adverse health effects of perfluoroalkyls to support their position.

Earthjustice submitted documents in opposition to a new PFAS premanufacture notice. The submission includes information on the climate impacts of hydrofluorocarbons (HFCs) and a technical report on reference dose and reference concentration processes.