Comment submitted by Buzz Biolabs, Inc.

The future of crop protection belongs to precision. We can no longer afford broad-spectrum tools that indiscriminately harm the ecosystems they are meant to protect. Species-specific technologies represent a decisive step forward — eliminating the target pest while leaving non-target organisms untouched. As a precision instrument within integrated pest management, this approach does more than add another option to the toolbox; it strengthens the entire system, relieving selection pressure and safeguarding the long-term effectiveness of the tools growers already depend on. I strongly support its registration. Genetic technologies such as Agragene are at the leading edge of this transformation. They deliver something conventional chemistry cannot: a genuinely environmentally responsible solution that spares non-target organisms entirely. This is not an incremental improvement — it is a fundamentally cleaner way to protect our crops. The benefits reach far beyond the field. Every reduction in chemical pesticide use means fewer residues in our food chain, translating into real and lasting gains for public health and for society as a whole. These are the kinds of generational benefits that justify decisive regulatory action today. Finally, the promise of this platform extends well beyond a single crop or a single pest. The same technology can be readily adapted to confront other urgent threats — including the invasive screwworm now endangering the cattle industry. Approving this registration is not merely about one product; it is about unlocking a versatile, powerful, and safe approach to protecting American agriculture for decades to come.